The LIU LAB
Electron Tomography at Yale University
Grant Supports
We are very grateful that our research projects are supported by NIGMS, NIAID, NIH, and Yale.
Postdoctoral Positions available
Interested candidates should have a Ph.D. in microbiology, biophysics or a related field. Please contact Dr. Liu along with CV, statement of research interests, and contact information for three references.
What Inspires Us
Louis Armstrong: "What a Wonderful World".
Apple's "Think Different" commercial: "Here's to the Crazy Ones".
Steve Jobs' 2005 Stanford Commencement Address: "Stay Hungry, Stay Foolish".
Charles Darwin: "It is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is the most adaptable to change."
State-of-the-art cryo-ET/EM facility at Yale University
We are fortunate to have access to state-of-the-art cryo-ET/EM facility at Yale University, including cryo-CLEM, cryo-FIB, 200kv Glacios, and 300kV Krios.
Contact
Journal Covers
High-throughput cryo-ET/EM pipelines
Cryo-ET and in-situ cryo-EM are among the most advanced technologies to visualize molecular machines in situ at high resolution. We aim to streamline the high-throughput cryo-ET/EM pipelines for high resolution imaging of molecular machines and cells.
Our laboratory is dedicated to developing high-throughput cryo-electron tomography (cryo-ET) and in-situ cryo-electron microscopy (in-situ cryo-EM) pipelines for high-resolution visualization of molecular machines in their native cellular environment. Our state-of-the-art imaging pipelines have been utilized to gain molecular insights into fundamental processes in microbiology: bacterial motility, chemotactic signaling, protein secretion, DNA translocation, and host-pathogen interactions.